Completely reversed acute rejection is not a significant risk factor for the development of chronic rejection in renal allograft recipients

Autoimmune retinopathy after chronic renal allograft rejection.

tient’s baseline anticoagulant therapy contributed to the unusually slow progression of vision loss. A few reports propose beneficial effects of anticoagulation and antiplatelet therapy in GCA-related vision loss. Buono et al reported improvement in acuity and posterior ciliary artery blood flow with the addition of heparin sodium therapy in a patient with progressive visual loss despite cortic...

Soluble CD30 and Acute Renal Allograft Rejection

Chronic allograft rejection: A significant hurdle to transplant success

The state-of-the-art immunosuppression drugs do not ensure indefinite transplant survival, and most transplants are continuously lost to chronic rejection even years posttransplantation. This form of rejection is responsible for long-term failure of transplanted organs. The mechanisms involved in development of chronic rejection are not well-understood. One of the main features of chronic rejec...

The role of chemokines in acute renal allograft rejection and chronic allograft injury.

Short and long term outcome of renal transplantation are determined by acute and chronic rejection processes. In acute transplant rejection, expression of chemokines occurs in different renal compartments where it is triggered through various stimuli e.g. brain death, ischemia, reperfusion, and HLA-mismatch. The induction of chemokine expression precedes the process of organ recovery and extend...

Acute and Chronic Lung Allograft Rejection

Over the last decade, lung transplantation has become a 'viable option for patients with end-stage lung disease. Due to the relatively small number of lung transplants done nationally, little experience has been gained in the outcome and management of pregnancies in the post-lung transplant patient, and little published data exist to assist the patient's physician regarding issues related to pr...